| AAMI | age-associated memory impairment |
| AD | Alzheimer’s disease |
| AKAP | A-kinase-anchoring proteins |
| AMP | adenosine monophosphate |
| cAMP | cyclic adenosine monophosphate |
| cGMP | cyclic guanosine monophosphate |
| CNS | central nervous system |
| COPD | chronic obstructive pulmonary disease |
| COX | cyclooxygenase |
| CR | conserved region |
| CREB | cAMP response element-binding protein |
| CUS | chronic unpredictable stress |
| ERK | extracellular signal-regulated kinase |
| GMP | guanosine monophosphate |
| HARBS | high-affinity Rolipram binding state |
| HCC | hepatocellular carcinoma |
| IFN | interferon |
| IL | interleukin |
| iNOS | inducible nitric oxide synthase |
| LARBS | Low-affinity Rolipram binding state |
| LPS | lipopolysaccharide |
| MAS | McCune–Albright syndrome |
| MS | multiple sclerosis |
| PAMPA | parallel artificial membrane permeability assay |
| PDE | phosphodiesterase |
| PDE4 | phosphodiesterase 4 |
| PDE4I | phosphodiesterase 4 inhibitor |
| PKA | protein kinase A |
| RACK1 | receptor for activated C kinase 1 |
| ROS | reactive oxygen species |
| TNF | tumor necrosis factor |
| UCR | upstream-conserved region |