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Direct comparison between the measured IDIF and AIF for a representative subject. The IDIF—is unaffected by tubing and measurement device transit times, unlike the AIF—was first delay-corrected to the AIF. Dispersion was subsequently added to the IDIF by convolution with the fitted time constant. In general, excellent agreement between the two input functions was found, with an average relative agreement of AUC of −0.3%.
