Table 1.

Summary of recommendations from various societies for colorectal cancer screening.

	ACG 2021	USMSTF 2022	ACS 2018	USPSTF 2021	NCCN 2022	ACP 2023
Age	Begin avg risk at 45 years	Begin avg risk at 45 years	Begin avg risk at 45 years	Begin avg risk at 45 years	Begin avg risk at 45 years	Begin avg risk at 50 years
All	50–75 years	50–75 years	50–75 years	50–75 years	50–75 years	50–75 years
75–85 years	Selectively	Selectively	Selectively	Selectively	Selectively	Discontinue at 75 years if life expectancy is 10 years or less
85+ years	Discourage screening	-	Discourage screening	Discourage screening	Discourage screening	-
Stool Based
gFOBT	-	-	Annual	Annual	Annual	Every 2 years
FIT	Annual	Annual	Annual	Annual	Annual	Every 2 years
mt-sDNA	Every 3 years	Every 3 years	Every 1–3 years	Every 1–3 years	Every 3 years	-
Endoscopic
Flexible Sigmoidoscopy	Every 5–10 years	Every 5–10 years	Every 5 years or Every 10 years if combined with FIT	Every 5 years	Every 5 years or Every 10 years if combined with FIT	Every 10 years + FIT every 2 years
Colonoscopy	Every 10 years	Every 10 years	Every 10 years	Every 10 years	Every 10 years	Every 10 years
CT Colonography	Every 5 years	Every 5 years	Every 5 years	Every 5 years	Every 5 years	-
Colon Capsule	Every 5 years	If the patient refuses all of the above	-	-	-	-

ACG: American College of Gastroenterology; USMSTF: United State Multi-Society Task Force; ACS: American Cancer Society; USPSTF: United States Preventive Services Task Force; NCCN: National Comprehensive Cancer Network; ACP: American College of Physicians; gFOBT: guaiac fecal occult blood test; FIT: fecal immunohistochemical test; mt-sDNA: Multi-Target Stool DNA.