Table 1.
Characteristics of the primary cancer in patients with isolated chest wall recurrences (CWRs).
| Clinical Features of Primary Cancer N = 194 | Patients with No Axillary Surgery at CWR N = 181/(%) |
Patients with Sentinel Lymph Node Biopsy and/or Axillary Lymph Node Dissection at CWR N = 13/(%) |
p Value |
|---|---|---|---|
| Age (years) | 0.022 | ||
| <50 | 86 (47.5) | 11 (84.6) | |
| ≥50 | 95 (52.5) | 2 (15.4) | |
| Reconstruction | 0.067 | ||
| Yes | 47 (26.1) | 7 (53.8) | |
| No | 133 (73.9) | 6 (46.2) | |
| Unknown | 1 | 0 | |
| Axillary surgery | 0.129 | ||
| Not done | 3 (1.7) | 1 (7.7) | |
| Sentinel lymph node biopsy | 53 (29.6) | 6 (46.2) | |
| Axillary lymph node dissection | 123 (68.7) | 6 (46.2) | |
| Unknown | 2 | 0 | |
| Tumour histology | 0.007 | ||
| Ductal carcinoma in situ | 12 (6.6) | 4 (30.8) | |
| Invasive ductal | 143 (79.0) | 7 (53.8) | |
| Invasive lobular | 15 (8.3) | 0 (0) | |
| Others | 11 (6.1) | 2 (15.4) | |
| Pathological features | |||
| Invasive tumour size (mm) 1 | 0.585 | ||
| ≤20 | 73 (46.5) | 5 (62.5) | |
| >20 to ≤50 | 74 (47.1) | 3 (37.5) | |
| >50 | 10 (6.4) | 0 (0) | |
| Not applicable/Unknown | 24 | 5 | |
| Grade of invasive cancer | 0.703 | ||
| I | 20 (12.8) | 2 (22.2) | |
| II | 84 (53.8) | 4 (44.4) | |
| III | 52 (33.3) | 3 (33.3) | |
| Not applicable/Unknown | 25 | 4 | |
| Oestrogen receptor (ER) 2 | 1.000 | ||
| Positive | 134 (82.7) | 7 (87.5) | |
| Negative | 28 (17.3) | 1 (12.5) | |
| Not applicable/Unknown | 19 | 5 | |
| Progesterone receptor (PR) 2 | 0.610 | ||
| Positive | 115 (72.8) | 7 (87.5) | |
| Negative | 43 (27.2) | 1 (12.5) | |
| Not applicable/Unknown | 23 | 5 | |
| Human epidermal growth factor receptor 2 (HER2) 2 | 1.000 | ||
| Positive | 37 (27.0) | 2 (33.3) | |
| Negative | 100 (73.0) | 4 (66.7) | |
| Not applicable/Unknown | 44 | 7 | |
| Nodal status | 0.063 | ||
| pN0 | 109 (62.6) | 12 (92.3) | |
| pN+ | 65 (37.4) | 1 (7.7) | |
| Unknown | 7 | 0 | |
| Chemotherapy 2 | 0.708 | ||
| Yes | 77 (45.6) | 3 (33.3) | |
| No | 92 (54.4) | 6 (66.7) | |
| Not applicable/Unknown | 12 | 4 | |
| Radiotherapy | 0.203 | ||
| Yes | 32 (17.7) | 0 (0.0) | |
| No | 149 (82.3) | 13 (100.0) | |
| Hormonal therapy | 0.636 | ||
| Yes | 130 (71.8) | 8 (61.5) | |
| No | 51 (28.2) | 5 (38.5) |
1 If multifocal/centric disease was present, the size measurement was based on the largest lesion. 2 Invasive cancer only.