Table 1.
A comparison of the anti-platelet activity of the extract from raw and roasted sea buckthorn seeds (5 µg/mL), and the extract from aronia berries (5 µg/mL) in washed blood platelets (measured by adhesion to adhesive proteins (collagen and fibrinogen)) and in whole blood (measured by T-TAS and flow cytometry).
| Sea Buckthorn Raw Seeds | Sea Buckthorn Roasted Seeds | Aronia Berries | |
|---|---|---|---|
| Inhibition of adhesion of thrombin-activated platelet to collagen | No effect | Anti-platelet activity | Anti-platelet activity | 
| Inhibition of adhesion of thrombin-activated platelet to fibrinogen | No effect | Anti-platelet activity | No effect | 
| Inhibition of thrombus formation (measured by T-TAS) | No effect | Anti-platelet activity | No effect | 
| Inhibition of the exposition of the active form of GPIIb/IIIa on 10 µM ADP—stimulated blood platelets | Anti-platelet activity | Anti-platelet activity | Anti-platelet activity | 
| Inhibition of the exposition of the active form of GPIIb/IIIa on 20 µM ADP—stimulated blood platelets | Anti-platelet activity | No effect | Anti-platelet activity | 
| Inhibition of the exposition of P-selectin on 10 µM ADP—stimulated blood platelets | No effect | No effect | No effect | 
| Inhibition of the exposition of P-selectin on 20 µM ADP—stimulated blood platelets | Anti-platelet activity | No effect | Anti-platelet activity |