Fig. 3.

Relative metabolism-associated gene expression in psoas muscle of wild-type (WT) C57Bl/6J and dysferlin-deficient BLA/J mice aged 5 months, without and with dexamethasone (Dex) treatment. A Glucose transporter type 4 (Glut4); B Lipoprotein lipase (Lpl); C Sterol regulatory element-binding transcription factor 1 (Srebf1); D Peroxisome proliferator-activated receptor gamma (Pparγ); E CCAAT/enhancer-binding protein delta (Cepbδ); F Fatty Acid Synthase (Fasn); G ATP citrate lyase (Acly); H Acetyl-CoA carboxylase 1 (Acaca). Skeletal actin (Acta1) was used as a reference gene to normalise gene expression values in the psoas muscle. Relative gene expression was calculated using the 2^−ΔΔCT Method, and values were normalised to the untreated WT for each gene. Data were analysed by two-way ANOVA: **, ***, **** BLA/J (± Dex) vs WT (± Dex) (p < 0.01, 0.001, 0.0001, respectively, strain effect). Data are log₁₀ transformed and presented on a log₁₀ y-axis scale as mean ± SD (n = 5–8)