Table 2.

Research Interest of Ped-unPAD study.

1. Incidence and minimal prevalence of unPAD in Italian scenario

2. Median age at disease onset and symptoms at onset

3. Median age at diagnosis (time span from clinical onset to clinical diagnosis to quantify diagnostic delay)

4. Clinical–immunological profile at diagnosis and during follow-up

5. Treatment performed and patient’s response

6. Genetic Characterization

7. Quality of Life