Table 3.
Comparison of Area Under the Curve and Receiver Operator Curves, Optimal Cutoff, and Diagnostic Accuracies of Different MR Quantitative Parameters Associated With NYHA Functional Class III-IV, LA Dilatation, or Pulmonary Hypertension
| Echo-EROA (mm2) |
Echo-RegVol (ml) |
CMR-RegVol (ml) |
CMR-RegFrac (%) |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Women | Men | Women | Men | Women | Men | Women | Men | ||
| NYHA functionalclass III-IV | AUC(95% CI)P value | 0.63 (0.51-0.76) P = 0.016 | 0.58 (0.50-0.66) P = 0.032 | 0.56 (0.44-0.68) P = 0.169 | 0.53 (0.45-0.62) P = 0.205 | 0.60 (0.48-0.71) P = 0.051 | 0.54 (0.46-0.62) P = 0.136 | 0.65 (0.54-0.76) P = 0.006 | 0.58 (0.50-0.66) P = 0.024 |
| Optimal cutoff value | 39 | 49 | NA | NA | NA | NA | 49 | 50 | |
| Sensitivity/specificity | 72/62 | 63/50 | NA | NA | NA | NA | 66/68 | 62/63 | |
| indLAV ≥60 ml/m2 | AUC(95% CI)P value | 0.52 (0.40-0.64) P = 0.355 | 0.61 (0.54-0.68) P < 0.001 | 0.57 (0.46-0.69) P = 0.110 | 0.64 (0.58-0.71) P < 0.001 | 0.66 (0.55-0.77, P = 0.003 | 0.67 (0.60-0.73) P < 0.001 | 0.65 (0.54-0.76) P = 0.005 | 0.64 (0.57-0.70) P < 0.001 |
| Optimal cutoff value | NA | 50 | NA | 74 | 50 | 67 | 47 | 50 | |
| Sensitivity/specificity | NA | 63/59 | NA | 67/57 | 73/61 | 63/66 | 64/61 | 60/63 | |
| RV peak pressure gradient ≥50 mm Hg | AUC(95% CI)P value | 0.61 (0.44-0.78) P = 0.138 | 0.57 (0.43-0.71) P = 0.151 | 0.56 (0.41-0.70) P = 0.274 | 0.60 (0.48-0.72) P = 0.063 | 0.64 (0.51-0.77) P = 0.062 | 0.63 (0.50-0.76) P = 0.023 | 0.75 (0.62-0.89) P = 0.003 | 0.69 (0.57-0.80) P = 0.002 |
| Optimal cutoff value | NA | NA | NA | NA | NA | 70 | 54 | 53 | |
| Sensitivity/specificity | NA | NA | NA | NA | NA | 64/59 | 73/76 | 68/68 | |