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Threshold effect analysis of the relationship between UHR and circulating α-klotho
| Results of threshold effect analysis | Outcome | P-value |
|---|---|---|
| Model 1 | - | - |
| one-line effect | -4.1 (-5.4, -2.7) | <0.001 |
| Model 2 | - | - |
| Break point (K) | 8.2 | - |
| < K | -15.0 (-20.9, -9.0) | <0.001 |
| > K | -2.8 (-4.3, -1.3) | <0.001 |
| Difference in effect before and after the breakpoint | 12.2 (5.7, 18.7) | <0.001 |
| α-klotho content at the folding point | 862.0 (852.6, 871.4) | - |
| Logarithmic likelihood ratio test P-value | - | < 0.001 |
