Table 5.
Subgroup analyses of the association between UHR and serum α-klotho
| Subgroup | β(95% CI) | P for interaction |
|---|---|---|
| Male | -2.8 (-4.4, -1.1) | 0.0058 |
| Female | -6.3 (-8.4, -4.2) | |
| Age < 60 | -4.5 (-6.3, -2.8) | 0.3878 |
| Age > 60 | -3.6 (-5.4, -1.8) | |
| Drinking | -4.2 (-5.7, -2.7) | 0.7155 |
| No Drinking | -3.7 (-6.1, -1.4) | |
| Smoking | -3.7 (-5.4, -2.1) | 0.4771 |
| No Smoking | -4.5 (-6.4, -2.7) | |
| BMI < 25 | -8.0 (-11.3, -4.7) | 0.0010 |
| BMI:25–30 | -3.5 (-5.8, -1.2) | |
| BMI > 30 | -2.3 (-4.0, -0.5) | |
| CVD | -6.6 (-10.8, -2.3) | 0.2230 |
| No CVD | -3.9 (-5.3, -2.4) | |
| DM | -4.7 (-7.3, -2.1) | 0.5408 |
| No DM | -3.8 (-5.3, -2.3) | |
| Cancer | -2.1 (-5.6, 1.4) | 0.2236 |
| No Cancer | -4.4 (-5.8, -3.0) | |
| HTN | -4.0 (-5.7, -2.4) | 0.9115 |
| No HTN | -4.2 (-6.0, -2.3) | |
| Stroke | -3.0 (-8.2, 2.3) | 0.6781 |
| No Stroke | -4.1 (-5.5, -2.7) | |
| CKD | -3.8 (-7.4, -0.2) | 0.8855 |
| No CKD | -4.1 (-5.5, -2.6) |
Note BMI: Body Mass Index, CVD: Cardiovascular Disease, DM: Diabetes Mellitus, HTN: Hypertension, CKD: Chronic Kidney Disease