Table 6.
Multivariable regression analysis of UHR and circulating α-klotho in unmedicated population
| Exposure | Model1 | Model2 | Model3 | |||
|---|---|---|---|---|---|---|
| β(95% CI) | P | β(95% CI) | P | β(95% CI) | P | |
| UHR | -6.1 (-7.5, -4.6) | < 0.001 | -4.2 (-5.8, -2.6) | < 0.001 | -4.2 (-6.2, -2.3) | < 0.001 |
| UHR T1: 1.35–8.12 | ref | ref | ref | |||
| UHR T2: 8.12–12.26 | -42.8 (-60.0, -25.7) | < 0.001 | -32.8 (-50.4, -15.3) | < 0.001 | -33.3 (-53.1, -13.4) | < 0.001 |
| UHR T3: 12.26–37.05 | -65.2 (-82.3, -48.0) | < 0.001 | -41.3 (-60.3, -22.2) | < 0.001 | -40.9 (-63.7, -18.1) | < 0.001 |
| UHR groups trend | -6.9 (-8.8, -5.1) | < 0.001 | -4.3 (-6.3, -2.2) | < 0.001 | -4.1 (-6.6, -1.6) | < 0.001 |
Note Model 1:unadjusted; Model 2: adjust for gender, age, race; Model 3: adjust for gender, age, race, marital status, Income-poverty ratio, BMI, education, smoking, drinking, eGFR, VD, CVD, DM, HTN, Cancer, CKD, Stroke