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There is an increase in the TGF-β/BMP signaling component pMad at kis mutant and APP and BACE expressing NMJs. (A,B) High-resolution confocal micrographs of the 6/7 NMJ of genotypes listed showing synaptic pMad (green) and HRP (magenta), which labels the presynaptic motor neuron. Fluorescence intensities, relative to controls, are depicted in right histograms. Scale bars = 5 µm. ** = p < 0.01, F = 9.24.
