Figure 1.

Immunohistochemistry of ADRA2A in the human testis. (A,B) In representative human testicular samples of two mixed atrophy patients, ADRA2A staining is found in peritubular, myoid cells (arrows in (B)) building the wall of seminiferous tubules and in interstitial cells, presumably Leydig cells (LC in (B)). Nuclei were slightly stained with hematoxylin. (C) When the first antibody was substituted by an IgG isotype antibody, a slight and faint overall brownish staining was observed in an additional third donor sample. Scale bars 50 µm.