Fig. 1. Meningiomas comprise three methylation clusters.
(A) Heatmap of methylation data for the signature probes of each methylation cluster. (B) t-distributed stochastic neighbor embedding (t-SNE) of our cohort and the meningiomas from the Heidelberg CNS tumor classifier (22) across our signature probes. (C) Heatmap of methylation data for the MM-FAV (favorable) and MM-UNFAV (unfavorable) probes from Olar et al. (13) across our three methylation clusters.