Table 2.

Examples of potential medical effects of 2,5-DMP.

Effects of 2,5-DMP	Sources of 2,5-DMP	Mechanisms	Experimental Species	References
Affect reproductive and accessory reproductive organs	ND 1	Reduce uterus weight	Female rats	[61]
Affect reproductive and accessory reproductive organs	ND	Decrease the weight of prostate, seminal vesicles, and testosterone levels in plasma	Male rats	[62]
Affect plasma testosterone and polyamines and acid phosphatase levels	ND	Decrease plasma testosterone and levels of polyamines and acid phosphatase in the prostate	Juvenile male rats	[63]
Affect uterine contraction	ND	Inhibit the late phase of pregnant uterine movements	Female rats	[65]
Induce sperm-head abnormalities	Purchased from Sigma-Aldrich (St. Louis, MO, USA); released by female CBA mice	Induce genetic damage during meiotic divisions	Highly inbred male CBA mice	[66]
Affect the concentration of plasma non-esterified fatty acid	ND	Suppress the non-esterified fatty acid rebound induced by nicotinic acid	Male Wistar rats	[67]
Affect the concentration of blood lipids	ND	Decrease blood lipid concentrations	Male Wistar rats	[68]

¹: ND, no data.