Resource Table

Unique stem cell lines identifier	1. BFVSBi003-A 2. BFVSBi004-A
Alternative name(s) of stem cell lines	1. VS-18 2. VS-19
Institution	Baszucki Family Vascular Surgery Biobank
Contact information of distributor	Dr. Nazish Sayed sayedns@stanford.edu
Type of cell lines	iPSC
Origin	Human
Additional origin info (Applicable for human ESC or iPSC)	1. BFVSBi003-A; Age:49, Sex: Female; Ethnicity: Caucasian 2. BFVSBi004-A; Age:53, Sex: Female; Ethnicity: Caucasian
Cell Source	PBMCs
Clonality	Clonal
Method of reprogramming	Integration-free Sendai virus expressing human OCT4, SOX2, KLF4, and c-MYC
Genetic Modification	Yes
Type of Genetic Modification	Spontaneous mutation
Evidence of the reprogramming transgene loss	RT/q-PCR
Associated disease	vascular Ehlers-Danlos Syndrome (vEDS)
Gene/locus	1. COL3A1 (c.226A > G, p.Asn76Asp)
Date archived/stock date	1. BFVSBi003-A: 12-17-2023 2. BFVSBi004-A: 11-23-2023
Cell line repository/bank	1. https://hpscreg.eu/cell-line/BFVSBi003-A 2. https://hpscreg.eu/cell-line/BFVSBi004-A
Ethical approvals	The Administrative Panel approved the generation of the lines on Human Subjects Research (IRB) under IRB #62122, “Human Induced Pluripotent Stem Cells for Studying Cardiac and Vascular Diseases.”