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. 2000 Nov 1;28(21):4189–4196. doi: 10.1093/nar/28.21.4189

Figure 6.

Figure 6

A speculative model for Gro-mediated repression. (A) Multiple transcription factors can individually or synergistically recruit Gro to the DNA template. Gro in turn recruits a histone deacetylase activity. (B) Polymerization of Gro along the chromatin template facilitated by interactions with deacetylated histones allows the establishment of a large transcriptionally-silent domain.