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A. ICR mice were injected via the tail vein with 5x105 cells of ERG251/ERG251 (SC5314), erg251Δ/ERG251, ERG251/erg251Δ, and erg251Δ/Δ+ERG251-A and erg251Δ/Δ+ERG251-B and survival was presented over the time. The erg251Δ/Δ mutant survival curves were significantly attenuated from that of the ERG251/ERG251 (Log-rank (Mantel-Cox) test; **, p = 0.0015). Eight mice per strain were used.
