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Survival analysis. (A) Intracranial PFS as per RECIST assessed by investigator and (B) OS from full analysis set. (C) Intracranial PFS as per RANO-LM criteria assessed by BICR and (D) OS from LM evaluable for response set. BICR, blinded independent central review; LM, leptomeningeal metastases; OS, overall survival; PFS, progression-free survival; RANO-LM, response assessment in neuro-oncology leptomeningeal metastases.
