Table 4.
Basic characteristics of SNPs associated with systemic lupus erythematosus and endometrial cancer
| SNP | EA | EAF | SLE | Endometrial cancer | ||||
|---|---|---|---|---|---|---|---|---|
| β | SE | P | β | SE | P | |||
| rs10048743 | T | 0.844516 | − 0.231112 | 0.0412056 | 2.04E−08 | − 0.0315 | 0.0342 | 0.3577 |
| rs10200680 | T | 0.170542 | − 0.248461 | 0.0424835 | 4.96E−09 | − 0.009 | 0.0323 | 0.781399 |
| rs1078324 | A | 0.0771133 | − 0.71335 | 0.0781665 | 7.11E−20 | 0.0425 | 0.0431 | 0.3236 |
| rs10912578 | G | 0.677349 | − 0.24686 | 0.0309918 | 1.65E−15 | − 0.0068 | 0.0266 | 0.7992 |
| rs1143679 | A | 0.105716 | 0.582216 | 0.0399866 | 5.03E−48 | − 0.0808 | 0.0503 | 0.1087 |
| rs12094036 | C | 0.0863467 | − 0.328504 | 0.0578595 | 1.37E−08 | − 0.0682 | 0.0437 | 0.1185 |
| rs12524498 | T | 0.117898 | − 0.673345 | 0.120793 | 2.48E−08 | 0.0229 | 0.0489 | 0.639501 |
| rs13019891 | T | 0.400861 | − 0.562119 | 0.0290336 | 1.65E−83 | 0.0205 | 0.0271 | 0.4494 |
| rs13136219 | T | 0.352739 | − 0.174353 | 0.027787 | 3.50E−10 | 0.0031 | 0.0263 | 0.9056 |
| rs13332649 | G | 0.216229 | − 0.314711 | 0.0375683 | 5.43E−17 | − 0.0353 | 0.0316 | 0.2638 |
| rs143123127 | A | 0.0346371 | 0.470004 | 0.0840342 | 2.23E−08 | − 0.1 | 0.0977 | 0.3059 |
| rs1464446 | T | 0.229049 | − 0.328504 | 0.0401497 | 2.79E−16 | − 0.0303 | 0.0289 | 0.2946 |
| rs150180633 | T | 0.00953749 | 0.928219 | 0.0689573 | 2.66E−41 | − 0.033 | 0.1287 | 0.7977 |
| rs17849501 | T | 0.0478014 | 0.81093 | 0.0498642 | 1.81E−59 | 0.0059 | 0.0715 | 0.9343 |
| rs2431697 | C | 0.370733 | − 0.223144 | 0.0292964 | 2.60E−14 | 0.0406 | 0.0269 | 0.1318 |
| rs2459611 | T | 0.916883 | 0.261365 | 0.045245 | 7.62E−09 | − 0.0987 | 0.0556 | 0.0757897 |
| rs2573219 | C | 0.110974 | 0.587787 | 0.0429292 | 1.13E−42 | 0.0512 | 0.038 | 0.1778 |
| rs268124 | T | 0.732828 | 0.18633 | 0.0323703 | 8.60E−09 | 0.0534 | 0.0298 | 0.0728098 |
| rs28361029 | A | 0.04887 | − 0.385662 | 0.0613604 | 3.27E−10 | − 0.1415 | 0.1412 | 0.3163 |
| rs34703115 | C | 0.0359907 | − 0.616186 | 0.104778 | 4.08E−09 | 0.0264 | 0.0629 | 0.6743 |
| rs35000415 | T | 0.124007 | 0.587787 | 0.041539 | 1.86E−45 | 0.0222 | 0.0471 | 0.6364 |
| rs35251378 | A | 0.311653 | − 0.235722 | 0.0324266 | 3.61E−13 | 0.0102 | 0.0268 | 0.702901 |
| rs353608 | G | 0.555886 | 0.18633 | 0.0280198 | 2.93E−11 | − 9.00E−04 | 0.0255 | 0.973 |
| rs3747093 | A | 0.283658 | 0.262364 | 0.0345055 | 2.88E−14 | − 0.0155 | 0.028 | 0.578599 |
| rs389884 | G | 0.120317 | 0.928219 | 0.0432319 | 2.92E−102 | − 0.0094 | 0.0479 | 0.8445 |
| rs4274624 | T | 0.749751 | − 0.559616 | 0.0326791 | 9.73E−66 | 0.0235 | 0.0282 | 0.4053 |
| rs4388254 | T | 0.0619589 | 0.378436 | 0.0603977 | 3.71E−10 | − 0.056 | 0.0528 | 0.289 |
| rs4661543 | G | 0.895557 | 0.274437 | 0.0423755 | 9.40E−11 | − 0.0471 | 0.041 | 0.2507 |
| rs4916215 | T | 0.789526 | 0.223144 | 0.0339693 | 5.07E−11 | − 0.0161 | 0.0322 | 0.6157 |
| rs58688157 | G | 0.208705 | − 0.223144 | 0.0335647 | 2.97E−11 | 0.0391 | 0.034 | 0.25 |
| rs58721818 | T | 0.0348105 | 0.65752 | 0.0755941 | 3.38E−18 | 0.0145 | 0.0631 | 0.8181 |
| rs597808 | G | 0.537926 | − 0.162519 | 0.0294736 | 3.51E−08 | 0.0531 | 0.0309 | 0.0856407 |
| rs6671847 | A | 0.427853 | 0.198851 | 0.0289651 | 6.64E−12 | − 0.0151 | 0.0269 | 0.5756 |
| rs6679677 | A | 0.116299 | 0.336472 | 0.0464854 | 4.55E−13 | − 0.0811 | 0.0485 | 0.0942996 |
| rs6889239 | C | 0.344668 | 0.277632 | 0.03174 | 2.19E−18 | − 0.013 | 0.0282 | 0.645199 |
| rs7097397 | A | 0.429586 | − 0.18633 | 0.0287118 | 8.60E−11 | 0.0223 | 0.0258 | 0.3879 |
| rs73050535 | T | 0.0179842 | − 0.71335 | 0.124134 | 9.11E−09 | − 0.0732 | 0.1119 | 0.5128 |
| rs73068668 | A | 0.0778141 | − 0.314711 | 0.0574903 | 4.40E−08 | 0.0664 | 0.0575 | 0.2488 |
| rs7768653 | T | 0.589676 | − 0.207014 | 0.0296891 | 3.11E−12 | − 0.0184 | 0.0253 | 0.4675 |
| rs7823055 | T | 0.513081 | − 0.350657 | 0.0286208 | 1.64E−34 | − 0.0163 | 0.0259 | 0.5298 |
| rs7899626 | T | 0.36465 | 0.182322 | 0.0332532 | 4.19E−08 | − 0.0248 | 0.0261 | 0.3418 |
| rs9852014 | G | 0.112948 | 0.620577 | 0.0492727 | 2.26E−36 | − 0.0596 | 0.0393 | 0.1296 |
EA, effect allele; EAF, effect allele frequency