Table 2. Unadjusted Means of Subjective Effect Ratings by Nicotine Form, Concentration, and Flavor at 35 Minutes.
| Variable | Rating, mean (95% CI)a | ||||
|---|---|---|---|---|---|
| Wanting | Liking | Enjoyment | Pleasure | Satisfaction | |
| Nicotine form | |||||
| Salt | 38.8 (35.6-41.9) | 42.8 (39.4-46.1) | 43.3 (40.0-46.6) | 45.2 (41.9-48.4) | 45.6 (42.4-48.8) |
| Freebase | 29.5 (26.5-32.5) | 32.0 (28.6-35.3) | 32.3 (29.0-35.7) | 32.8 (29.5-36.0) | 35.4 (32.3-38.5) |
| Nicotine concentration, % | |||||
| 1 | 38.8 (35.8-41.8) | 43.4 (40.2-46.6) | 43.9 (40.7-47.1) | 44.3 (41.2-47.4) | 43.2 (40.1-46.3) |
| 5 | 29.3 (26.1-32.5) | 31.2 (27.7-34.6) | 31.5 (28.2-34.9) | 33.4 (30.0-36.8) | 37.6 (34.3-41.0) |
| Flavor | |||||
| Menthol | 38.9 (35.7-42.1) | 43.2 (39.7-46.7) | 43.2 (39.8-46.7) | 44.3 (40.9-47.7) | 44.9 (41.6-48.1) |
| Tobacco | 29.4 (26.4-32.3) | 31.5 (28.4-34.7) | 32.4 (29.2-35.6) | 33.6 (30.5-36.7) | 36.1 (33.0-39.2) |
a
Ratings were on a scale of 0 to 100, with higher ratings indicating more positive subjective effects. All estimates showed a significant difference between the 2 conditions of nicotine form, concentration, and flavor in generalized linear mixed models.