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. 2024 Aug 9;7(8):e2426702. doi: 10.1001/jamanetworkopen.2024.26702

Table 3. Unadjusted Means of Puffing Topography Measures by Nicotine Form, Concentration, and Flavor.

Variable Measure, mean (95% CI)
Total puff count, No. Puff duration, s Interpuff interval, s Volume per puff, mL Total puff volume, mL Velocity, mL/S
Nicotine form
Salt 16.0 (14.4-17.6)a 3.0 (2.8-3.1)a 117.7 (106.3-129.1) 46.4 (43.5-49.3)a 785.2 (702.4-868.1)a 16.8 (16.0-17.7)
Freebase 14.2 (12.6-15.8)a 2.9 (2.8-3.0)a 123.9 (109.8-138.0) 42.2 (40.1-44.4)a 742.3 (664.2-820.4)a 17.7 (16.6-18.8)
Nicotine concentration, %
1 17.1 (15.5-18.7)a 3.1 (3.0-3.3)a 115.1 (102.6-127.5)a 49.4 (46.6-52.2)a 900.6 (813.5-987.6)a 17.3 (16.5-18.2)
5 13.1 (11.6-14.6)a 2.7 (2.6-2.8)a 126.9 (114.0-139.8)a 38.7 (36.8-40.7)a 608.8 (543.8-673.8)a 17.2 (16.1-18.3)
Flavor
Menthol 15.2 (13.7-16.8) 3.0 (2.8-3.1)a 114.8 (103.7-125.8) 44.8 (42.5-47.1) 757.3 (684.9-829.7) 16.9 (16.1-17.8)
Tobacco 15.0 (13.3-16.6) 2.9 (2.8-3.1)a 126.6 (112.4-140.7) 43.9 (41.1-46.6) 773.1 (683.8-862.3) 17.5 (16.5-18.6)
a

Significant difference between the 2 conditions of nicotine form, concentration, and flavor in generalized linear mixed models.