Figure 3. Effect of TT on RBC characteristics and indices of hemolysis in cold storage.

Leukocyte-reduced RBC units collected from 21 donors on testosterone replacement therapy (TT) and 20 controls were stored for six weeks and evaluated weekly for A. Percent storage hemolysis. B. Percent oxidative hemolysis. C. Extracellular potassium (K+) concentration (mmol/L). D. Lactate concentration (mmol/L). E. Percent oxygen saturation (sO2). F. Red cell distribution width-coefficient of variation (RDW-CV). *, p < 0.05; ***, p < 0.001. Mean±SD. p values obtained from Prism’s multivariable mixed-effects model with Fisher’s LSD test. A, B, F, N=21 TT and 20 Controls. C, D, E, N=17–18 TT and 16–17 Controls.