Figure 4. Effect of TT on RBC posttransfusion recovery in immunodeficient mice.

Stored (39–42 days) leukocyte-reduced RBC units collected donors on testosterone replacement therapy (TT) and matched controls were transfused into immunodeficient mice (NSG), as detailed in Materials and Methods. A. Percent RBC posttransfusion recovery in non-irradiated RBCs (N=16 TT and N=15 controls). B. Gamma-irradiated RBCs (N=8 TT and N=7 controls). Mean±SD. **; p=0.0034 from Prism’s multivariable mixed-effects model with Fisher’s LSD test.