Table 2.

Logistic regression analysis of the associations of body mass index and total body fat with chronic kidney disease in participants of the Netherlands Epidemiology of Obesity (NEO) study

		Crude		Model 1a		Full modelb
	N	OR	95% CI	OR	95% CI	OR	95% CI
Chronic kidney diseasec
BMI, per 1 kg/m2	6671	1.08	1.05 to 1.10	1.08	1.05 to 1.11	1.08	1.05 to 1.11
Total body fat, per 1%	6640	1.03	1.01 to 1.05	1.06	1.03 to 1.08	1.05	1.02 to 1.08
eGFRd < 60 ml/min/1.73m2
BMI, per 1 kg/m2	6621	1.03	0.99 to 1.07	1.03	0.99 to 1.08	1.02	0.98 to 1.07
Total body fat, per 1%	6590	1.02	0.99 to 1.05	1.02	0.98 to 1.06	1.01	0.97 to 1.05
Moderately increased albuminuriae
BMI, per 1 kg/m2	6644	1.11	1.08 to 1.14	1.11	1.08 to 1.15	1.11	1.08 to 1.15
Total body fat, per 1%	6613	1.03	1.01 to 1.06	1.08	1.05 to 1.12	1.08	1.05 to 1.12

Results were based on analyses weighted towards the body mass index distribution of the general population.

CI confidence interval, eGFR estimated glomerular filtration rate, BMI body mass index

^aAdjusted for age, sex, smoking and ethnicity.

^bModel 1 plus additional adjustment for physical activity and Dutch Healthy Diet index

^cDefined as having an eGFR <60 mL/min/1.73 m² and/or moderately increased albuminuria

^dCreatinine-based eGFR calculated using the 2012 CKD Epidemiology Collaboration (CKD-EPI) equation, taking into account age, sex, and race

^eModerately increased albuminuria is defined as urine albumin-to-creatinine ratio ≥ 2.5 mg/mmol in men and ≥ 3.5 mg/mmol in women