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. 2024 Aug 10;14:18602. doi: 10.1038/s41598-024-68299-6

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Immuno-expression of Nrf2 in aorta sections in the different groups: (A) Control group, the aorta shows marked cytoplasmic expression in muscle layer (×400). (B) Long chain saturated fat diet group, the aorta shows moderate cytoplasmic expression in tunica media (arrow) (×400). (C) Long chain monounsaturated fat diet group, the aorta shows moderate nuclear (arrow) and mild cytoplasmic (arrowhead) expression in tunica media (×400). (D) Long chain polyunsaturated fat diet group, the aorta shows marked nuclear (arrow) and mild cytoplasmic (arrowhead) expression in tunica media (×400). (E) Medium chain fat diet group, the aorta shows mild nuclear (arrows) and cytoplasmic (arrowhead) expression in muscle layer (×400). (F) Short chain fat diet group, the aorta shows moderate nuclear (arrows) and mild cytoplasmic (arrowheads) expression in tunica media (×400).