Figure 1.

Functional analysis: Treadmill testing and EKG analysis of chagasic and uninfected mice. (A, B) Distance run and time of exercise on a motorized treadmill involving mice after 6 and 12 months of infection, respectively; Representative EKG images: (C) EKG of an uninfected mouse with regular sinus rhythm; (D) EKG of a chagasic mouse with total atrioventricular block; (E) EKG of chagasic mouse with polymorphic ventricular tachycardia. * = P wave; # = QRS complex. Treadmill test: Values represent means ± S.E.M. of 10 and 14 mice (6 months of infection) and 7 and 8 mice (12 months of infection) from uninfected and chagasic groups, respectively. ***P< 0.001 compared to uninfected group.