Figure 4.

Co-staining with Cx43 and N-Cadherin in hearts of chagasic mice and uninfected controls. (A, B) Non-infected hearts show the presence of Cx43 (green) and N-cadherin (red) in the intercalated disk area; (C, D) chagasic hearts frequently presented N-cad exclusively in intercalated disc areas, with Cx43 dispersed into the cytoplasm. White arrows indicate Cx43 in cytoplasm, while white asterisks indicate intercalated discs with only N-cad expression. N-cad, N-cadherin; Cx43, Connexin 43. Scale bars = 25 µm.