Table 1.

Description of GWAS data sources for each phenotype.

Dataset type	Variable	GWAS ID	Sample size	Consortium	Population	Sex
Exposure	Dietary habits	See Supplementary Table S1		MRC-IEU	European	Males and females
	Body mass index	ieu-a-2	339,224	GIANT	European	Males and females
	Age at menopause	ieu-a-1004	69,360	ReproGen	European	Females
	Age at menarche	ieu-a-1095	182,416	ReproGen	European	Females
	Age of Smoking Initiation	ieu-b-24	341,427	GSCAN	European	Males and females
Outcome	BC, breast cancer	ieu-a-1126	228,951	BCAC	European	Females
	BC (ER+), estrogen receptor positive breast cancer	ieu-a-1127	175,475	BCAC	European	Females
	BC (ER−), estrogen receptor negative breast cancer	ieu-a-1128	127,442	BCAC	European	Females
	EC, endometrial cancer	ebi-a-GCST006464	121,885	ECAC/E2C2/UKB	European	Females
	EC (EH), endometrial cancer (endometrioid histology)	ebi-a-GCST006465	54,884	ECAC/E2C2/UKB	European	Females
	EC (EH), endometrial cancer (non-endometrioid histology)	ebi-a-GCST006466	36,677	ECAC/E2C2/UKB	European	Females
	LC, lung cancer	ieu-a−966	27,209	ILCCO	European	Males and females
	LUAD, lung adenocarcinoma	ieu-a-965	18,336	ILCCO	European	Males and females
	LUSC, lung squamous carcinoma	ieu-a-967	18,313	ILCCO	European	Males and females
	OC, ovarian cancer	ieu-a−1,120	66,450	OCAC	European	Females
	OC (HGS), high grade serous ovarian cancer	ieu-a-1121	53,978	OCAC	European	Females
	OC (LGS), low grade serous ovarian cancer	ieu-a-1122	41,953	OCAC	European	Females
	OC (IM), invasive mucinous ovarian cancer	ieu-a-1123	42,358	OCAC	European	Females
	OC (CC), invasive mucinous ovarian cancer	ieu-a-1124	42,307	OCAC	European	Females
	OC (ED), endometrioid ovarian cancer	ieu-a-1125	43,751	OCAC	European	Females
	PC, prostate cancer	ieu-b-85	140,254	PRACTICAL	European	Males