Table 2.
Significant and nominal significant MR results of FDR correction.
| Outcome | Exposure | SNP(n) | IVW | WM | MR-Egger | ||||
|---|---|---|---|---|---|---|---|---|---|
| OR (95%CI) | p-value | FDR | OR (95%CI) | P-value | Intercept | P-value | |||
| BC | Dried fruit intake | 149 | 0.80(0.68,0.94) | 7.66E-03 | 2.31E-01 | 0.76(0.63,0.90) | 2.20E-03 | 2.12E-03 | 5.40E-01 |
| BC | Fresh fruit intake | 134 | 0.78(0.64,0.95) | 1.34E-02 | 2.31E-01 | 0.80(0.61,1.04) | 9.40E-02 | -5.36E-05 | 9.85E-01 |
| BC | Cheese intake | 187 | 0.89(0.80,0.98) | 2.05E-02 | 2.31E-01 | 0.86(0.76,0.97) | 1.53E-02 | 1.16E-03 | 6.71E-01 |
| BC (ER+) | Fresh fruit intake | 133 | 0.79(0.64,0.97) | 2.61E-02 | 5.86E-01 | 0.76(0.55,1.05) | 1.30E-01 | 2.60E-03 | 3.76E-01 |
| BC (ER+) | Cheese intake | 184 | 0.88(0.79,0.99) | 2.88E-02 | 5.86E-01 | 0.90(0.78,1.03) | 9.85E-02 | −4.10E-04 | 8.91E-01 |
| BC (ER+) | Cereal type: Bran cereal (e.g., All Bran, Branflakes) | 11 | 2.93(1.05,8.14) | 3.96E-02 | 5.86E-01 | 1.87(0.49,7.20) | 3.61E-01 | -8.00E-04 | 9.23E-01 |
| BC (ER−) | Cheese intake | 186 | 0.78(0.68,0.91) | 1.34E-03 | 3.02E-02 | 0.91(0.74,1.12) | 3.82E-01 | 3.16E-04 | 9.37E-01 |
| BC (ER−) | Dried fruit intake | 150 | 0.73(0.58,0.91) | 5.38E-03 | 6.49E-02 | 0.70(0.51,0.95) | 2.27E-02 | −1.89E-03 | 6.90E-01 |
| BC (ER−) | Cereal intake | 165 | 0.77(0.63,0.93) | 6.46E-03 | 6.49E-02 | 0.78(0.59,1.03) | 8.46E-02 | -1.48E-03 | 7.12E-01 |
| EC (EH) | Cheese intake | 203 | 0.71(0.54,0.91) | 8.21E-03 | 1.85E-01 | 0.54(0.38,0.76) | 4.62E-04 | -9.71E-03 | 1.70E-01 |
| LC | Alcohol usually taken with meals | 130 | 0.45(0.29,0.71) | 5.72E-04 | 2.58E-02 | 0.42(0.22,0.80) | 7.73E-03 | -1.04E-02 | 1.93E-01 |
| LC | Average weekly beer plus cider intake | 73 | 1.74(1.09,2.77) | 1.92E-02 | 4.08E-01 | 1.71(0.94,3.09) | 7.79E-02 | -1.40E-02 | 1.37E-01 |
| LC | Processed meat intake | 88 | 1.47(1.04,2.08) | 2.72E-02 | 4.08E-01 | 1.81(1.13,2.89) | 1.29E-02 | -4.48E-03 | 6.33E-01 |
| LUSC | Alcohol usually taken with meals | 119 | 0.46(0.22,0.96) | 3.77E-02 | 9.27E-01 | 0.42(0.15,1.17) | 9.66E-02 | -1.53E-02 | 2.42E-01 |
| OC (HGS) | Dried fruit intake | 144 | 0.75(0.56,1.00) | 4.94E-02 | 5.97E-01 | 0.84(0.55,1.28) | 4.16E-01 | 4.53E-04 | 9.41E-01 |
| OC (HGS) | Non-oily fish intake | 57 | 1.64(1.00,2.67) | 4.94E-02 | 5.97E-01 | 2.39(1.19,4.82) | 1.48E-02 | −3.69E-03 | 6.54E-01 |