Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Aug 11;14:18632. doi: 10.1038/s41598-024-69597-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

PMC Copyright notice

Behavior. Open field. (a) The scatter plots show the time spent in the center of the open field and the distanced traveled for each of the experimental conditions. Shown are the mean ± SD. The single dose LSD was significantly greater than vehicle or multiple dose for time spent in the center (*p < 0.05). Novel object preference. (b) Shown are scatter plots of the investigation ratio (time spent investigating the novel object/time spent investigating both objects). Performance was compared to chance (i.e., IR = 0.5) using single-sample, two-tailed t-tests. All experimental conditions were better than chance (****p < 0.0001). The latency to explore the novel object immediately after introduction to the chamber was significantly less for the multiple treatments as compared to vehicle and single treatment (*p < 0.05) The bout duration or time spent with the familiar objects at one exploration encounter was significantly greater for multiple treatments as compared to the other conditions (*p < 0.05). Shown are the mean ± SD.