Figure 3.

Global functional connectivity. (a) The percentage change in degrees (connections) for all 139 brain areas between multidose LSD and vehicle controls are shown as violin plots for vehicle and multidose LSD treatments. The multidose treatment showed mean difference (MD) of 6.96 percent less than vehicle and had significantly fewer connections (two-tailed, paired t-test, p < 0.0001). When the 139 brain areas were organized into 12 brain regions (Supplementary Data Fig S1), there were no significant differences in degrees between vehicle and multidose groups with the exception of the somatosensory cortex (b). (b) The mean ± SD for the number of degrees in the somatosensory cortex for veh as compared to the multidose group. (**p < 0.01).