Table 3. Association of hypertension (HT) with BMI, basic biochemical parameters, oxidative stress and inflammation markers in children with nephrotic syndrome in the acute phase.

Data are presented as median with interquartile range. The comparison was performed by the Mann–Whitney U test. LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TC, total cholesterol; TG, triglycerides; AOPP, advanced oxidation protein products; PAB, prooxidant-antioxidant balance; TOS, total oxidant status; PON1, paraoxonase 1; -SH, sulfhydryl groups; TAS, total antioxidant status; PTX 3, pentraxin 3; E-cad, E cadherin; PD-L1, programmed death ligand 1. P < 0.05 was considered statistically significant.

Parameters	Patients with HT (n=8)	Patients without HT (n=25)	P-value
BMI, kg//m2	18.6 (18.7–20.1)	17.8 (16.8–18.6)	0.074
Glucose, mmol/L	4.6 (3.7–6.4)	5.33 (4.5–6.1)	0.429
Urea, mmol/L	4.4 (3.3–11.7)	4.0 (3.2–5.5)	0.472
Creatinine, μmol/L	27.5 (24–47)	34.0 (28.3–40.5)	0.420
Total proteins, g/L	42 (37–51)	41 (39–47.8)	0.831
Albumin, g/L	10 (7.5–14.8)	10.5 (7.3–18.5)	0.711
TC, mmol/L	10.7 (7.4–12.5)	9.4 (6.7–11.3)	0.384
LDL-C, mmol/L	7.9(5.0–10.1)	7.0(4.4–8.8)	0.443
HDL-C, mmol/L	1.1 (1.0–1.4)	1.4 (0.9–1.8)	0.119
TG, mmol/L	2.5 (1.5–3.1)	1.8 (1.1–2.8)	0.286
TAS, μmol/L	814.09 (702.07–975.40)	832.35 (745.21–951.70)	0.684
TOS, μmol/L	17.35 (11.68–20.85)	8.70 (7.70–12.00)	0.003
AOPP, μmol/L	67.15 (56.89.90–86.55)	44.60 (36.33–53.93)	0.029
SH, mmol/L	0.31 (0.12–0.50)	0.22 (0.16–0.34)	0.395
PON1, U/L	256.5 (250.5–1352.8)	531.5 (263.5–934.5)	0.760
PAB, HKU	129.4 (122.25–174.15)	162.58 (127.35–297.70)	0.201
PTX 3, ng/mL	5.48 (4.56–10.51)	4.81 (3.17–7.12)	0.241
Leptin, ng/mL	0.29 (0.16–0.58)	0.46 (0.26–1.89)	0.140
E-cad, ng/L	549.00(521.00–634.00)	669.92(518.00–744.00)	0.250
PDL-1, ng/L	129.17(29.17–250.83)	45.84(98.33–262.92)	0.561