Figure 8.

In silico immune system simulations using the C-ImmSim service include the following observations: (A) Increases in IgM and IgG responses (depicted as a cream peak) and a reduction in antigen levels (black peak) were noted after the second and third injections. (B) Activation of the B-cell population is shown by a purple peak. (C) Boosting of B cells for memory functions is indicated by a green peak. (D) TH cell activation is represented by a purple peak. (E) The enhancement of memory TH cells is shown as a green peak. (F) The T-cell response showing Th1 polarization is depicted with a purple peak. (G) Increases in IL-2 (cream peak) and IFN-γ (purple peak) in response to the vaccine.