Table 2.
Summary of PCV (%) and PPE in T. haneyi-infected horses during treatment (Tx) with BPQ
| Weeks post-Tx | HO-270 | HO-364 | HO-776 | HO-777 | HO-784 | HO-411 | HO-413 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PCV | PPE | PCV | PPE | PCV | PPE | PCV | PPE | PCV | PPE | PCV | PPE | PCV | PPE | |
| 0a | 50.1 | 0 | 45.1 | 0 | 40.3 | 0 | 42.6 | 0 | 36.9 | 0 | 35.9 | 0 | 46.5 | 0 |
| 1 | 44.3 | 0 | 44.2 | 0 | 32.7 | 0 | 37.9 | 0 | 34.9 | 0 | 41.8 | 0 | 44.8 | 0 |
| 2 | 44.9 | 0 | 40.7 | 0 | 39.1 | 0 | 43.0 | 0 | 39.8 | 0 | 45.1 | 0 | 40.0 | 0 |
| 3 | 49.3 | 0 | 43.8 | 0 | 40.4 | 0 | 41.2 | 0 | 37.8 | 0 | 47.0 | 0 | 45.1 | 0 |
| 4 | 44.0 | 0 | 41.9 | 0 | 40.2 | 0 | 40.2 | 0 | 39.3 | 0 | 40.0 | 0 | 47.0 | 0 |
| 5 | 42.5 | 0 | 39.8 | 0 | 43.5 | 0 | 39.6 | 0 | 42.1 | 0 | 47.0 | 0 | 40.0 | 0 |
| 6 | 45.2 | 0 | 42.3 | 0 | 42.6 | 0 | 41.1 | 0 | 39.7 | 0 | 45.0 | 0 | 47.0 | 0 |
| 7 | 47.9 | 0 | 48.2 | 0 | 39.8 | 0 | 44.5 | 0 | 42.5 | 0 | 41.0 | 0 | 45.0 | 0 |
| 8 | 44.9 | 0 | 47.4 | 0 | 36.5 | 0 | 40.7 | 0 | 34.8 | 0 | 37.0 | 0 | 41.0 | 0 |
| 9 | 42.8 | 0 | 42.6 | 0 | 40.6 | 0 | 36.9 | 0 | 37.0 | 0 | 35.0 | 0 | 40.0 | 0 |
| 10 | 48.0 | 0 | 42.6 | 0 | 45.6 | 0 | 41.8 | 0 | 42.9 | 0 | nt | 0 | nt | 0 |
| 11 | 50.2 | 0 | 36.8 | 0 | 40.3 | 0 | 39.3 | 0 | 34.7 | 0 | nt | 0 | nt | 0 |
| 12 | 41.5 | 0 | 41.2 | 0 | 34.7 | 0 | 33.1 | 0 | 35.5 | 0 | nt | 0 | nt | 0 |
| 13 | 69.4 | 0 | 37.3 | 0 | 36.0 | 0 | 33.8 | 0 | 34.8 | 0 | nt | 0 | nt | 0 |
| 14 | 42.0 | 0 | 41.0 | 0 | 46.2 | 0 | 36.7 | 0 | 33.1 | 0 | nt | 0 | nt | 0 |
| 15 | 36.5 | 0 | 40.5 | 0 | 36.9 | 0 | 38.4 | 0 | 34.8 | 0 | 42.8 | 0 | 40.9 | 0 |
| 16 | 36.8 | 0 | 38.5 | 0 | 37.1 | 0 | 38.0 | 0 | 34.3 | 0 | nt | 0 | nt | 0 |
| 17 | 36.9 | 0 | 43.0 | 0 | 39.1 | 0 | 39.0 | 0 | 29.3 | 0 | nt | 0 | nt | 0 |
| 18a | 37.6 | 0 | 38.6 | 0 | 38.1 | 0 | 42.2 | 0 | 33.1 | 0 | nt | 0 | nt | 0 |
| 19b | 44.7 | 0 | 43.5 | 0 | 32.6 | 0 | 39.3 | 0 | 31.4 | 0 | 40.7 | 0 | 39.3 | 0 |
| 20 | 39.4 | 0 | 37.5 | 0 | 34.5 | 0 | 36.0 | 0 | 36.0 | 0 | nt | nt | nt | 0 |
| 21 | 41.3 | 0 | 41.3 | 0 | 43.9 | 0 | 37.6 | 0 | 38.1 | 0 | nt | nt | nt | nt |
| 22 | 42.4 | 0 | 42.4 | 0 | 33.5 | 0 | 36.7 | 0 | 34.4 | 0 | nt | nt | nt | nt |
| 23 | 43.0 | 0 | 43.0 | 0 | 36.2 | 0 | 36.1 | 0 | 37.6 | 0 | 40 | 0 | 33.6 | 0 |
| 24 | 40.6 | 0 | 40.6 | 0 | 47.9 | 0 | 44.8 | 0 | 47.4 | 0 | nt | nt | nt | nt |
| 25 | 51.0 | 0 | 54.1 | 0 | 42.9 | 0 | 40.3 | 0 | 40.5 | 0 | nt | nt | nt | nt |
| 26 | 43.8 | 0 | 49.3 | 0 | 45.3 | 0 | 44.3 | 0 | 47.8 | 0 | nt | nt | nt | nt |
| 27 | 48.1 | 0 | 52.7 | 0 | 44.4 | 0 | 43.2 | 0 | 42.4 | 0 | 38.5 | 0 | 40.1 | 0 |
| 28 | 46.9 | 0 | 48.7 | 0 | 36.3 | 0 | 41.4 | 0 | 39.6 | 0 | nt | nt | nt | nt |
| 29 | 47.0 | 0 | 48.9 | 0 | 41.7 | 0 | 44.3 | 0 | 43.5 | 0 | nt | nt | nt | nt |
| 30 | 45.0 | 0 | 43.7 | 0 | 46.6 | 0 | 38.5 | 0 | 44.8 | 0 | nt | nt | nt | nt |
| 31 | 43.4 | 0 | 51.3 | 0 | 43.9 | 0 | 39.3 | 0 | 37.1 | 0 | nt | nt | nt | nt |
| 32 | 41.9 | 0 | 49.3 | 0 | 41.8 | 0 | 42.3 | 0 | 39.7 | 0 | nt | nt | nt | nt |
| 33 | 48.6 | 0 | 41.6 | 0 | 37.6 | 0 | 38.7 | 0 | 41.3 | 0 | nt | nt | nt | nt |
| 34 | spl | nt | nt | nt | spl | nt | nt | nt | nt | nt | nt | nt | nt | nt |
| 35 | 35.8 | nt | nt | nt | 32.0 | nt | nt | nt | nt | nt | nt | nt | nt | nt |
spl splenectomy, nt not tested
aRepresents the time of treatment at 0 and 18 weeks
bRepresents treatment of HO-784 at 19 weeks post-treatment with 6 mg/kg of BPQ