Table 1.
Cohort characteristics of subjects with surgical CoA and without CoA
| Total cohort (N = 110) | No CoA (N = 85) | CoA (N = 25) | p value | |
|---|---|---|---|---|
| Maternal age | 32.0±5.4 | 32.2±5.8 | 31.7±4.3 | 0.66 |
| Race/ethnicity, n (%) | White/Caucasian: 38 (35) | White/Caucasian: 29 (34) | White/Caucasian: 9 (36) | 0.97 |
| Hispanic: 32 (29) | Hispanic: 25 (29) | Hispanic: 7 (28) | ||
| Asian: 25 (22) | Asian: 19 (22) | Asian: 6 (24) | ||
| Black/African American: 3 (3) | Black/African American: 2 (2) | Black/African American: 1 (4) | ||
| Other: 2 (2) | Other: 2 (2) | Other: 0 | ||
| Unknown: 10 (9) | Unknown: 8 (9) | Unknown: 2 (8) | ||
| Indication for referral (CHD vs. screening)*, n (%) | 68 (62) | 48 (56) | 20 (80) | 0.03 |
| Average gestational age first fetal echo, weeks | 25.3±5.9 | 25.5±6.0 | 24.8±5.8 | 0.59 |
| Average gestational age last fetal echo, weeks | 31.9±3.6 | 31.9±3.6 | 32.4±3.5 | 0.57 |
| Fetal sex (female), n (%) | 47 (43) | 36 (42) | 11 (44) | 0.88 |
| Genetic/syndromic, n (%) | 14 (13)3 | 10 (12) | 4 (16) | 0.58 |
| Associated major CHD**, n (%) | 31 (28) | 18 (21) | 13 (52) | <0.01 |
| Estimated fetal weight, g | 1,627.7±640 | 1,628.9±645.8 | 1,734.7±574.9 | 0.46 |
| Estimated fetal Co., mL/kg/min*** | 366.2±175 | 383.6±167 | 346±174 | 0.34 |
| Excluded fetuses | 1 insufficient images, 1 loss to follow-up, 13 terminations/fetal demise | |||
*CHD, cases specifically referred for fetal echocardiography due to concern for congenital heart defect on obstetric ultrasound. Screening refers to other indications of perform a fetal echocardiogram.
**Structural cardiac anomalies which require surgical repair but do not confer dependency on PGE or neonatal intervention.
***Cardiac output.