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. 2024 Jul 15;15(8):1287–1297. doi: 10.1021/acsmedchemlett.4c00162

Scheme 7. Synthesis of Secondary Amine.

Scheme 7

Reaction conditions: (i) 1. 5, AcOH, THF/MeOH, 4 Å MS. 2. NaCNBH3; (ii) HCl, MeOH; (iii) AcOH, THF/MeOH, 4 Å MS. 2. NaCNBH3.