Table 2. Rate of gene evolution for rearranged (R) and colinear (C) chromosomes in humans versus chimpanzees or other primates.

Rate of evolution	Rearranged	Colinear	R/C
Human: chimpanzee (all genes, 109)
KA/KS	0.780 (54)	0.483 (55)	1.61
KA	0.007 (54)	0.005 (55)	1.40
KS	0.016 (54)	0.017 (55)	0.94
Human: chimpanzee (overlapping genes, 85)
KA/KS	0.820 (42)	0.581 (43)	1.41
KA	0.007 (42)	0.006 (43)	1.16
KS	0.016 (42)	0.014 (43)	1.14
Human: outgroup primates (overlapping genes, 85)
KA/KS	0.623 (42)	0.443 (43)	1.41
KA	0.031 (42)	0.024 (43)	1.30
KS	0.061 (42)	0.059 (43)	1.03

Data are from ref. 29. K_A and K_S are as defined in Table 1. Number of genes is given in parentheses.