Table 1.
Characteristics of the Included Studies
| Author, year, and country | Sample size |
FTIR spectroscopic technique | Specimen | Diagnostic performance |
Confusion matrix | NOS assessment |
|---|---|---|---|---|---|---|
| Miskovicova et al., 2020; Czech Republic | CRC: 30 | ATR-FTIR | Blood plasma | FTIR only | FTIR only: | High Quality |
| Healthy: 33 | Sn: 73.3% | TP: 22 | ||||
| Sp: 81.8% | FP: 6 | |||||
| Acc: 77.8% | FN: 8 | |||||
| TN: 27 | ||||||
| FTIR combined with ROA, ECD, Raman | FTIR combined with ROA, ECD, Raman | |||||
| Sn: 90% | TP: 27 | |||||
| Sp: 75.8% | FP: 8 | |||||
| Acc: 82.5% | FN: 3 | |||||
| TN: 25 | ||||||
| Toraman et al., 2019; Turkey | CRC: 30 | ATR-FTIR | Blood plasma | MLPNN: | MLPNN: | High Quality |
| Healthy: 40 | ||||||
| 1300-1000 cm-1 | 1300-1000 cm-1 | |||||
| Sn: 93.3% | TP: 28 | |||||
| Sp: 97.5% | FP: 1 | |||||
| Acc: 95.7% | FN: 2 | |||||
| TN: 39 | ||||||
| 1800-1300 cm-1 | ||||||
| Sn: 83.3% | 1800-1300 cm-1 | |||||
| Sp: 100% | TP: 25 | |||||
| Acc: 92.9% | FP: 0 | |||||
| FN: 5 | ||||||
| TN: 40 | ||||||
| SVM: | SVM: | |||||
| 1300-1000 cm-1 | 1300-1000 cm-1 | |||||
| Sn: 93.3% | TP: 28 | |||||
| Sp: 95.0% | FP: 2 | |||||
| Acc: 94.3% | FN: 2 | |||||
| TN: 38 | ||||||
| 1800-1300 cm-1 | ||||||
| Sn: 83.3% | 1800-1300 cm-1 | |||||
| Sp: 92.5% | TP: 25 | |||||
| Acc: 88.6% | FP: 3 | |||||
| FN: 5 | ||||||
| TN: 37 |