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. 2024 Jul 31;20(7):e1011950. doi: 10.1371/journal.ppat.1011950

Fig 4. EBNA-LP Leucine-rich motifs are important in transformation of cord blood B cells.

Fig 4

A. Total tdTomato positive cells at 21 days post infection for each cord blood donor in LPKO virus infected, trans-complemented cells (n = 3). P values from unpaired t-test. Mean and standard deviation are plotted. B. Total tdTomato positive cells from trans-complemented cord blood B cells at 28 or 35 days post infection weeks (n = 3). C. Number of tdTomato positive LCLs generated from trans-complemented LPKO infected cord blood B cells. #Indicates conditions in which some replicates generated tdTomato negative LCLs. +Indicates a tdTomato negative LCL which grew out slower compared to those trans-complemented with wild type EBNA-LP. P values calculated using Fisher’s exact test to compare transformation outcomes to LPKO + Vector. *** indicates a p value < 0.001.