FIG. 6.

Titers of MCMV mutants in salivary glands, lungs, spleens, livers, and kidneys of infected SCID mice. CB17 SCID mice were infected intraperitoneally with 10⁴ PFU of each virus. At 1, 3, 7, 10, 14, and 21 days postinfection, the animals (three mice per group) were sacrificed. The salivary glands, lungs, spleens, livers, and kidneys were collected and sonicated. Viral titers in the tissue homogenates were determined by standard plaque assays in NIH 3T3 cells. The limit of detection was 10 PFU/ml of the tissue homogenate. The values shown represent averages obtained from triplicate experiments; the error bars indicate standard deviations. Error bars that are not evident indicate that the standard deviation was less than or equal to the height of the symbols. WT, wild type.