TABLE 1.

Brief description of the clinically relevant functional tests included in this review.

Functional test	Brief description of test	Clinically‐relevant outcome
6‐min walk (6MWT)	Total distance walked without assistance over a 6‐min period	Indicator of cardiopulmonary and musculoskeletal response to exercise (Bellet et al., 2013; Karanth & Awad, 2017; Trudelle‐Jackson & Jackson, 2018)
Sit to stand	Number of “full stands from a seated position” (without using hands) completed in 30 s. May also be measured as the number of full stands from seated position in a fixed period of time.	Measure of lower extremity strength, balance, disability and falls risk (Bellet et al., 2013; Karanth & Awad, 2017; Trudelle‐Jackson & Jackson, 2018)
Grip strength	Subject maximally squeezes a hand grip dynamometer three times with each hand. Maximal grip of the three repetitions for each hand is recorded.	Surrogate measure of overall muscle strength (and lower grip strength has been associated with all‐cause mortality and disability) (Prasitsiriphon & Pothisiri, 2018; Puhan et al., 2008)
Timed up & go	Time it takes for a seated subject to stand, walk a set distance (e.g., 3 meters), walk back and sit back down.	A metric of lower extremity function, mobility and fall risk (Whitney et al., 2005; Witherspoon et al., 2018)