Table 2.
Baseline Characteristics of Male Rotterdam Study Participants, Including Individuals With and Without Migraine
| Male participants | All (n = 3,085) | With (a history of) migraine (n = 201) | Without (a history of) migraine (n = 2,884) |
| Aura (%) | 37 (1.2) | 37 (18.4) | — |
| Age (y) | 66.2 [56.2−74.5] | 61.4 [55.8−72.5] | 66.5 [56.2−74.6] |
| Education level (%) | |||
| Primary education | 237 (7.7) | 20 (10.0) | 217 (7.5) |
| Lower/intermediate general education or lower vocational education | 809 (26.2) | 58 (28.9) | 751 (26.0) |
| Intermediate vocational education or higher general education | 1,125 (36.5) | 60 (29.9) | 1,065 (36.9) |
| Higher vocational education or university | 914 (29.6) | 63 (31.3) | 851 (29.5) |
| BMI (kg/m2) | 27.2 [25.0−29.6] | 27.5 (3.3) | 27.1 [25.0−29.6] |
| Obesity (BMI >30 kg/m2) | 672 (21.8) | 40 (19.9) | 632 (21.9) |
| Waist-to-hip ratio | 0.94 [0.89−0.99] | 0.94 (0.08) | 0.94 [0.89−0.99] |
| Systolic blood pressure (mm Hg) | 141 [127−156] | 140 [127−154] | 141 [127.8−156] |
| Diastolic blood pressure (mm Hg) | 84 [77−91] | 83 [76−90] | 84 [77−91] |
| Hypertension (%) | 2,180 (70.7) | 141 (70.1) | 2039 (70.7) |
| Antihypertensive drug use (%) | 1,305 (42.3) | 94 (46.8) | 1,211 (42.0) |
| Total cholesterol (mmol/L) | 5.2 [4.5−5.9] | 5.2 (1.0) | 5.2 [4.5−5.9] |
| High-density lipoprotein cholesterol (mmol/L) | 1.3 [1.0−1.5] | 1.3 [1.0−1.5] | 1.3 [1.0−1.5] |
| Triglycerides (mmol/L) | 1.3 [1.0−1.8] | 1.4 [1.1−1.9] | 1.3 [1.0−1.8] |
| Hypercholesterolemia (%) | 1,457 (47.2) | 97 (48.3) | 1,360 (47.2) |
| Lipid-lowering medication use (%) | 989 (32.1) | 68 (33.8) | 921 (31.9) |
| Fasting glucose levels (mmol/L) | 5.5 [5.2−6.1] | 5.5 [5.2−6.2] | 5.5 [5.2−6.1] |
| Diabetes mellitus (%) | 439 (14.2) | 30 (14.9) | 409 (14.2) |
| Smoking status (%) | |||
| Former | 1819 (59.0) | 129 (64.2) | 1,690 (58.6) |
| Current | 533 (17.3) | 30 (14.9) | 503 (17.4) |
| Pack-years of ever smokers | 20.0 [8.0−36.8] | 20.0 [8.2−34.9] | 20.0 [8.0−37.0] |
| Alcohol consumption (gram/day) | 8.6 [1.6−20.0] | 6.4 [1.6−10.7] | 8.6 [1.6−20.0] |
| Physical activity (MET hours/week) | 34.8 [15.0−68.7] | 37.3 [18.0−70.3] | 34.5 [14.8−68.5] |
Abbreviations: BMI = body mass index; MET = metabolic equivalent of task.
Note: Imputed and unadjusted values of the cohort, with and without stratification for the migraine diagnosis, are displayed as means (SD) or medians [interquartile range, Q3–Q1] or as numbers (percentage). Shapiro-Wilk normality test was used to assess normality.