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. 2024 Jul 31;103(4):e209700. doi: 10.1212/WNL.0000000000209700

Table 4.

Associations of Categorical Cardiovascular Risk Factors With Migraine, Stratified by Sex

Cardiovascular risk factor Model 1 Model 2 Model 3
Female participants Male participants Female participants Male participants Female participants Male participants
Current smoking 0.68 [0.55−0.83] 0.78 [0.50−1.21] 0.72 [0.58−0.89] 0.82 [0.52−1.29] 0.72 [0.58−0.90] 0.84 [0.53−1.33]
Obesity 1.04 [0.87−1.24] 0.83 [0.56−1.23] 1.01 [0.84−1.20] 0.86 [0.58−1.29] 1.02 [0.85−1.22] 0.79 [0.51−1.20]
Hypercholesterolemia 1.07 [0.92−1.25] 0.99 [0.72−1.37] 1.09 [0.93−1.28] 1.02 [0.73−1.43] 1.11 [0.95−1.30] 0.99 [0.70−1.39]
Hypertension 1.08 [0.91−1.28] 1.18 [0.82−1.72] 1.08 [0.90−1.28] 1.20 [0.82−1.75] 1.08 [0.90−1.29] 1.24 [0.83−1.84]
Diabetes Mellitus 0.79 [0.60−1.03] 1.21 [0.77−1.90] 0.75 [0.57−0.99] 1.17 [0.74−1.85] 0.74 [0.56−0.98] 1.23 [0.76−1.99]

Model 1 is unadjusted.

Model 2 is adjusted for Rotterdam Study cohort, alcohol consumption, physical activity, and educational level.

Model 3 is adjusted for current smoking, obesity, hypercholesterolemia, hypertension, diabetes mellitus, Rotterdam Study cohort, alcohol consumption, physical activity, and educational level.