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. 2024 Jul 30;11:1390971. doi: 10.3389/fvets.2024.1390971

Figure 12.

Figure 12

Transverse plane T2-weighted images of the brain of a dog with L-2-hydroxyglutaric aciduria. Note the diffuse cortical grey matter swelling of the forebrain and cerebellum with increased signal intensity (A–E). There are bilateral and symmetrical lesions affecting the globus pallidus and putamen (long white arrows) (A), thalamus (long white arrow) and subthalamus (dashed long white arrows) (B), oculomotor nuclei (long white arrows) (C), lateral lemniscus (long white arrows) (D) and cerebellar nuclei (long white arrows) and vestibular nuclei (dashed long white arrows) (E). The subcortical white matter is also mildly affected (long black arrows).