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. 2024 Jul 22;56(8):1597–1603. doi: 10.1038/s41588-024-01839-y

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a, Overview of the phenotypes under investigation. Early bleeding occurs up to and until the 20th gestational week, antepartum bleeding occurs between the 20th gestational week and birth, and PPH occurs after birth. b, Manhattan plot of PPH showing the 18 M variants, with SNPs passing the functionally informed multiple testing criteria highlighted in green and labels with gene names for the genes indicated by the functional analysis. c, Miami plot comparing PPH caused by atony (top) and retained placenta (bottom). Green dots indicate SNPs passing the multiple testing threshold, and labels hold the gene names for the genes indicated by the functional analysis.