Extended Data Fig. 4. Association between COVID-19 risk variants and influenza infection in AncestryDNA (18,334 cases vs. 276,295 controls), biobank cohorts (22,022 cases vs. 1,131,269 controls) or overall meta-analysis (40,356 cases vs. 1,407,564 controls).

Of the 24 COVID-19 risk variants, 16 were discovered in a GWAS of COVID-19 hospitalization (comparing COVID-19 hospitalized cases against individuals with no record of SARS-CoV-2 infection), and 8 were discovered in a GWAS of reported SARS-CoV-2 infection (comparing all individuals with a record of SARS-CoV-2 infection against individuals with no record of SARS-CoV-2 infection). The association observed between the 24 variants and influenza infection was comparable between AncestryDNA, biobank cohorts and overall meta-analysis GWAS. Error bars represent the 95% confidence interval around the odds ratio (data point).