Table 1.
FGFR3 mutations in 75 invasive cervical carcinoma samples
Sample | Age | Stage | Histology | HPV | Codon | Mutation | Predicted effect |
6.96.1 | 65 | IB | SCC | + * | 249 | TCC → TGC | Ser → Cys |
4.139 | 69 | IIB | SCC | 33 | 249 | TCC → TGC | Ser → Cys |
4.13 | 64 | IIB | SCC | 16 | 249 | TCC → TGC | Ser → Cys |
7.79.1 | 58 | IIB | SCC | + * | 249 | TCC → TGC | Ser → Cys |
* Tumors with HPV DNA sequences of undetermined type (other than HPV 6, 11, 16, 18, 31, 33, 35, 39, 42, 45, 52 and 58). SCC : Squamous Cell Carcinoma