Table 2.
Correlations between hippocampal volumes and memory test in early relapsing remitting multiple sclerosis (RRMS) and subgroups assessed using Spearman test
| Whole hippocampus | Right hippocampus | Left hippocampus | |||||||
|---|---|---|---|---|---|---|---|---|---|
| RRMS | MMI-MS | SMI-MS | RRMS | MMI-MS | SMI-MS | RRMS | MMI-MS | SMI-MS | |
|
SRT-LTS r (p-value) |
0.194 (0.004) | 0.249 (0.009) | 0.176 (0.065) | 0.187 (0.006) | 0.257 (0.007) | 0.153 (0.113) | 0.191 (0.005) | 0.230 (0.017) | 0.190 (0.049) |
|
SRT-CLTR r (p-value) |
0.196 (0.004) | 0.257 (0.007) | 0.158 (0.099) | 0.199 (0.003) | 0.253 (0.008) | 0.169 (0.078) | 0.180 (0.008) | 0.250 (0.009) | 0.137 (0.156) |
|
SRT-DR r (p-value) |
0.207 (0.002) | 0.347 (< 0.001) | 0.133 (0.169) | 0.210 (0.002) | 0.365 (< 0.001) | 0.121 (0.210) | 0.193 (0.004) | 0.313 (0.001) | 0.135 (0.162) |
|
SPART r (p-value) |
0.077 (0.258) | 0.344 (< 0.001) | − 0.073 (0.452) | 0.081 (0.233) | 0.344 (< 0.001) | − 0.068 (0.485) | 0.068 (0.316) | 0.328 (0.001) | − 0.073 (0.451) |
|
SPART-DR r (p-value) |
0.115 (0.091) | 0.251 (0.009) | 0.040 (0.683) | 0.129 (0.058) | 0.242 (0.012) | 0.067 (0.470) | 0.095 (0.165) | 0.248 (0.010) | 0.007 (0.942) |
Bold values indicate significant differences
MMI mildly memory impaired, SMI severely memory impaired, SRT Selective Reminding Test, SRT-LTS long-term storage, SRT-CLTR consistent long-term retrieval, SRT-DR delay recall, SPART Spatial Recall Test, SPART-DR delay recall