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. 2002 Apr 15;30(8):1789–1798. doi: 10.1093/nar/30.8.1789

Figure 8.

Figure 8

The differential cell-specific USF stimulation results from the accessibility of the heptameric E-box within the lama3 gene. The lama3 heptameric E-box has been mutated to a gal4 binding site within PHA to give the PHAgal4 construct. (A) Transfection of KHSV and 804G, two lama3-expressing cell lines, and NIH-3T3 cells expressing the transactivating factor pM-53/pVP16-T along with the gal4 luc positive control construct are shown. (B) Transfection of KHSV, 804G and NIH-3T3 cells with pM-53, pVP16-T and either PHA, PHAgal4 or PHAgal4 mut ABC constructs are shown. Induction folds are relative to activities in the absence of the transactivating constructs.